See also:

Initialization
Items to initialize The following items must be initialized for normal system operation in cases such as after the 12-volt battery is reconnected, or maintenance is performed on the vehicle. ...

Have the vehicle inspected by your Lexus dealer immediately.
Failing to investigate the cause of the following warnings may lead to the system operating abnormally and possibly cause an accident. Have the vehicle inspected by your Lexus dealer immediately. ...

Using the steering wheel audio switches
Some audio features can be controlled using the switches on the steering wheel. 1, Increases/decreases volume 2, Radio mode: Selects a radio station CD mode: Selects a track, file (MP3 and WMA) a ...